SEPNAZ-SB 130

SEPNAZ-SB 130

COMPOSITION:

Itraconazole Capsules BP 130 mg

PACKING

10x 10 Capsules Alu/Alu

Description:

SEPNAZ-SB 130 is a potent broad-spectrum antifungal capsule containing Itraconazole 130 mg, designed to effectively treat systemic and superficial fungal infections. It works by inhibiting the synthesis of ergosterol, a vital component of the fungal cell membrane, thereby stopping fungal growth and promoting faster recovery.

This advanced antifungal therapy is widely prescribed for conditions like dermatophytosis, candidiasis, onychomycosis, and tinea infections. With enhanced bioavailability and once-daily convenience, SEPNAZ-SB 130 ensures effective control over persistent fungal infections and prevents recurrence.

Therapeutic Indications

SEPNAZ-SB 130 Capsules are indicated for the treatment of:

• Systemic and superficial fungal infections

• Dermatophytosis (ringworm infections) of skin, nails, and hair

• Onychomycosis (fungal nail infections)

• Vulvovaginal candidiasis

• Oropharyngeal and esophageal candidiasis

• Pityriasis versicolor (tinea versicolor)

• Histoplasmosis, Blastomycosis, Aspergillosis

• Tinea pedis (athlete’s foot), Tinea cruris, and Tinea corporis

Its broad antifungal spectrum makes it effective against Candida species, Aspergillus, Cryptococcus, Blastomyces, Histoplasma, and Dermatophytes.

Mechanism of Action

Itraconazole works by inhibiting fungal cytochrome P450–dependent enzyme lanosterol 14α-demethylase, which is crucial in the biosynthesis of ergosterol. Without ergosterol, the fungal cell membrane becomes weak and permeable, leading to cell death. This mechanism ensures a targeted and potent antifungal effect with minimal resistance.

Key Benefits of SEPNAZ-SB 130

✅ Broad-Spectrum Antifungal Activity – Effective against both superficial and systemic fungal infections.
✅ High Bioavailability – Ensures faster absorption and enhanced therapeutic results.
✅ Long-Lasting Action – Sustained effect allows for convenient once-daily dosing.
✅ Better Patient Compliance – Capsule form offers easy administration and improved adherence.
✅ Clinically Proven Safety – Well-tolerated with minimal side effects when taken as prescribed.

Dosage & Administration

• The usual adult dose is one capsule daily (or as directed by the physician).

• The dosage and duration of therapy depend on the type and severity of the infection.

• It should be taken after meals for maximum absorption.

Note: Always follow your doctor’s prescription for correct dosage and duration.

Precautions & Warnings

• Avoid in patients with known hypersensitivity to Itraconazole or other azole antifungals.

• Use cautiously in patients with liver impairment or heart failure.

• Not recommended during pregnancy or breastfeeding unless prescribed by a doctor.

• Do not consume alcohol or antacids within two hours of taking the capsule as they may reduce absorption.

Doctor’s Tip 💊

“Itraconazole 130 mg is one of the most trusted antifungal treatments. I recommend SEPNAZ-SB 130 for patients with resistant fungal infections, as its enhanced bioavailability and longer half-life ensure faster relief and reduced recurrence.”

Storage

Store in a cool, dry place below 25°C, away from direct sunlight and moisture. Keep out of reach of children.