ESMIK-DSR

COMPOSITION: Esomeprazole 40mg + Domperidine 30mg SR

PACKING: 10 x 10 (Alu-Alu)

Expert Advice for Esomeprazole 40 mg + Domperidone 30 mg SR

The combination of Esomeprazole (40 mg) and Domperidone (30 mg SR) is a widely prescribed medication to manage acid-related disorders, including GERD (Gastroesophageal Reflux Disease), acid reflux, and associated nausea or vomiting. This combination offers dual benefits: acid suppression by Esomeprazole and enhanced gastrointestinal motility by Domperidone.

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1. Key Benefits

Esomeprazole (40 mg)

• Proton Pump Inhibitor (PPI):
  • Reduces stomach acid by inhibiting proton pumps in the stomach lining.
• Treats Acid-Related Disorders:
  • Effective in managing GERD, peptic ulcers, and Zollinger-Ellison syndrome.
• Prevents Acid-Related Damage:
  • Protects the esophagus and stomach lining from acid-related injuries.

Domperidone (30 mg SR)

• Prokinetic Agent:
  • Promotes faster emptying of stomach contents by enhancing gut motility.
• Relieves Nausea and Vomiting:
  • Blocks dopamine receptors to reduce nausea and vomiting.
• Sustained Release (SR):
  • Provides prolonged relief by maintaining consistent blood levels throughout the day.

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2. Uses

• Management of GERD and heartburn.
• Relief from acid reflux and acid-induced esophagitis.
• Treatment of peptic ulcers caused by excessive stomach acid.
• Reduction of nausea and vomiting associated with delayed gastric emptying.
• Alleviation of symptoms like bloating, post-meal discomfort, and early satiety.

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3. How to Use

1. Dosage:
   • Generally, one tablet daily, 30 minutes before meals or as directed by your doctor.
2. Administration:
   • Swallow the tablet whole with water. Do not crush, chew, or split the tablet, as it disrupts the sustained-release mechanism.

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4. Precautions

1. Medical Conditions:
   • Inform your doctor if you have liver, kidney, or heart conditions.
2. Avoid Long-Term Use Without Supervision:
   • Prolonged use of Esomeprazole may lead to vitamin B12 deficiency, calcium loss, or increased fracture risk.
3. Pregnancy & Breastfeeding:
   • Consult your doctor before using during pregnancy or breastfeeding.
4. QT Prolongation Risk:
   • Domperidone can prolong QT intervals, so use cautiously if you have a history of heart arrhythmias.
5. Drug Interactions:
   • Avoid combining with drugs like ketoconazole, itraconazole, or warfarin without medical advice.

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5. Common Side Effects

Esomeprazole:

• Headache, diarrhea, nausea, and abdominal pain.
• Rarely, long-term use may lead to low magnesium levels or bone fractures.

Domperidone:

• Dry mouth, mild abdominal cramps, or dizziness.
• Rarely, it may increase prolactin levels, causing breast tenderness or irregular periods. Products Categories

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6. When to Consult a Doctor

• Persistent Symptoms:
  • If symptoms like heartburn or nausea continue despite regular use.
• Severe Side Effects:
  • Symptoms such as chest pain, irregular heartbeat, or persistent diarrhea require immediate medical attention.
• Allergic Reactions:
  • Rash, itching, swelling of the face, or difficulty breathing are signs of an allergy and need urgent care.

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7. Tips for Better Effectiveness

• Avoid Acid-Triggering Foods:
  • Limit spicy, fatty, and acidic foods to prevent symptoms.
• Adopt Healthy Eating Habits:
  • Eat smaller, frequent meals instead of large ones.
• Maintain an Upright Position After Meals:
  • Avoid lying down immediately after eating.
• Reduce Alcohol and Tobacco Use:
  • Both can aggravate acid reflux symptoms.

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8. Storage Instructions

• Store in a cool, dry place, away from direct sunlight and moisture.
• Keep the medication out of reach of children.

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9. Final Thoughts

Esomeprazole 40 mg + Domperidone 30 mg SR is an effective solution for managing GERD, acid reflux, and nausea. It offers comprehensive relief by addressing both acid suppression and motility issues. Use this medication as prescribed and combine it with a healthy lifestyle for optimal results. Always consult your doctor for personalized advice and regular monitoring.

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