MIRAZE-DSR

COMPOSITION: Pantoprazole- 40mg + Domperidone -30mg SR

PACKING: 10 x 10 (Alu-Alu)

Expert Advice for Pantoprazole 40 mg + Domperidone 30 mg SR

Pantoprazole 40 mg + Domperidone 30 mg SR is a combination medication primarily used to manage gastrointestinal disorders like GERD (Gastroesophageal Reflux Disease), acid reflux, and nausea. It combines the benefits of Pantoprazole, a Proton Pump Inhibitor (PPI), and Domperidone, a prokinetic agent with anti-nausea properties.

1. Key Benefits

Pantoprazole (40 mg)

• Acid Suppression:
  Reduces stomach acid by inhibiting proton pumps in the stomach lining.
• Protects Digestive Tract:
  Heals acid-induced damage to the esophagus and stomach, such as ulcers.
• Effective in GERD:
  Relieves heartburn, acid regurgitation, and discomfort caused by acid reflux.

Domperidone (30 mg SR)

• Improves Gut Motility:
  Enhances stomach and intestinal movements, promoting faster gastric emptying.
• Relieves Nausea and Vomiting:
  Blocks dopamine receptors, reducing nausea associated with delayed digestion or reflux.
• Sustained Release (SR):
  Ensures a prolonged effect for consistent relief throughout the day.

2. Uses

• Treatment of GERD and associated heartburn.
• Management of acid reflux and acid-induced stomach or esophageal ulcers.
• Relief from nausea and vomiting, especially related to gastric motility disorders.
• Reduces symptoms of bloating and post-meal discomfort.

3. How to Use

1. Dosage:
   Typically, one tablet is taken daily, 30 minutes before a meal, or as prescribed by your healthcare provider.
2. Administration:
   Swallow the tablet whole with water; do not crush, chew, or break it to preserve the sustained-release effect. Products Categories

4. Precautions

1. Medical History:
   • Inform your doctor if you have liver or kidney problems, or a history of heart conditions.
2. Avoid Long-Term Use Without Supervision:
   • Prolonged use of Pantoprazole may lead to calcium deficiency, B12 deficiency, or an increased risk of bone fractures.
3. Pregnancy & Breastfeeding:
   • Consult your doctor before taking this medication if you are pregnant or breastfeeding.
4. Drug Interactions:
   • Avoid taking with ketoconazole, itraconazole, or certain antibiotics without medical advice.
5. QT Prolongation Risk:
   • Domperidone may cause QT prolongation in susceptible individuals. Discuss this risk if you have a history of arrhythmias.

5. Common Side Effects

• Pantoprazole:
  • Headache, diarrhea, nausea, or abdominal pain.
  • Rarely, long-term use may lead to low magnesium levels or bone fractures.
• Domperidone:
  • Dry mouth, dizziness, or mild abdominal cramps.
  • Rare side effects include increased prolactin levels, which may cause breast tenderness or irregular periods.

6. When to Consult a Doctor

• Severe or Persistent Symptoms:
  • If symptoms like heartburn or nausea do not improve despite regular use.
• Allergic Reactions:
  • Symptoms like rash, swelling, or breathing difficulties need immediate attention.
• Severe Side Effects:
  • Persistent diarrhea, irregular heartbeat, or unusual fatigue should be reported immediately.

7. Tips for Better Effectiveness

• Dietary Adjustments:
  Avoid spicy, fatty, or acidic foods that can trigger GERD symptoms.
• Meal Timing:
  Eat smaller, frequent meals instead of large ones to prevent reflux.
• Stay Upright:
  Avoid lying down immediately after eating; wait for at least 2 hours.
• Avoid Triggers:
  Reduce intake of caffeine, alcohol, and tobacco.

8. Storage

• Store in a cool, dry place, away from direct sunlight and moisture.
• Keep out of reach of children.

Final Thoughts

Pantoprazole 40 mg + Domperidone 30 mg SR is a reliable solution for managing acid reflux, GERD, and nausea. Regular use as prescribed by your doctor, combined with healthy lifestyle choices, can significantly improve your symptoms and quality of life. Always consult your healthcare provider for personalized advice and long-term management.

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