S-Adenosyl-L-Methionine (SAMe) is a naturally occurring compound that is synthesized in the body from the amino acid methionine. It is involved in several biochemical reactions in the body, including the formation of neurotransmitters, DNA, and cartilage.
SAMe is available as a dietary supplement in capsule or tablet form. The typical recommended dose of SAMe is 400-1600 mg per day, although the optimal dose may vary depending on the individual and the condition being treated.
SAMe has been studied for its potential therapeutic effects in a variety of conditions, including depression, osteoarthritis, liver disease, and fibromyalgia. Some studies suggest that SAMe may be effective in reducing symptoms of depression and osteoarthritis, although more research is needed to confirm these findings.
SAMe may interact with certain medications, including antidepressants, and may not be appropriate for individuals with certain medical conditions, such as bipolar disorder or Parkinson’s disease.